Sofosbuvir and ribavirin in acute hepatitis C–infected patient with decompensated cirrhosis

نویسندگان

  • Hui Liu
  • Tong Zhang
  • Yan Yan
چکیده

BACKGROUND The treatment of chronic hepatitis C virus infection has been revolutionized by the advent of direct-acting antiviral agents. However, evidence of its effects on patients with acute hepatitis C (AHC) virus infection is limited. CASE SUMMARY We report the case of a patient with decompensated cirrhosis induced by autoimmune liver disease, whose condition rapidly deteriorated following AHC virus infection. The patient received sofosbuvir and ribavirin combination treatment for 12 weeks. Serum hepatitis C virus RNA remained undetectable 36 weeks after discontinuing sofosbuvir and ribavirin. CONCLUSION Our findings support the use of sofosbuvir and ribavirin as a treatment in AHC patients with decompensated cirrhosis.

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عنوان ژورنال:

دوره 95  شماره 

صفحات  -

تاریخ انتشار 2016